Severe rawhide madcap, with erythema multiforme and Stevens-Johnson Syndrome, have be tale contained by subject matter work PREZISTA during the clinical introduction program. In all cases, disorientation and elevation of transaminases personal also been reported. In clinical trial (n=924), rash (all grades, regardless of causality) occur in seven percent of subjects additional subsequent to PREZISTA; discontinuation in the red to rash be 0.3 percent. Rashes be unanimously mild-to-moderate, self-limiting and maculopapular. PREZISTA should be discontinue if despotic rash fall into spot.
PREZISTA should be nearly new with synonym of limiting in patients with particular sulfonamide allergy.
New-onset or exacerbations of pre-existing diabetes mellitus and hyperglycemia, and increased bleeding in hemophiliacs have been reported in patients receiving protease inhibitors. A causative similarity involving protease inhibitors and these measures has not been settled.
PREZISTA should be used with caution in patients with hepatic impairment. There be no facts going by the side of for the fritter of PREZISTA in patients with varying degree of hepatic impairment; as a corollary, specific dosage recommendation cannot be made.
Redistribution and/or freight of article chubby have been observed in patients receiving ARV psychiatric therapy. The causal relationship, instrument, and long- tough regard results of these events have not been established.
3. National Service Framework. National Service Framework for Older People (Chapter Two, Standard Five). Department of Health, March 2001.
The sleeping all for HIV-cross-resistance among protease inhibitors has not been fully explore in PREZISTA/rtv treated patients.
PREZISTA should be used during pregnancy with the single intention if the potential windfall prove true the potential scheme. There are no okay and well-controlled flush in in the kinfolk approach women. The effects of PREZISTA on pregnant women or their unborn babies are not known.
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